9. MUSCULOSKELETAL DISORDERS

Written and reviewed by Dr. Saint Paul | Pharm.D Graduate from JNTUK | Pharmacy Educator and D.Pharmacy Academic Content Creator

Musculoskeletal disorders affect muscles, bones, joints, and connective tissues. They commonly cause pain, stiffness, swelling, and reduced mobility.

This guide explains two major conditions — Rheumatoid Arthritis and Osteoarthritis — including their causes, symptoms, and management.

Rheumatoid arthritis is an autoimmune disorder where the immune system attacks joints, causing inflammation and damage.

  • Seropositive RA
  • Seronegative RA
  • Juvenile RA
  • Joint pain and swelling
  • Morning stiffness
  • Fatigue
  • Weight loss
  • Exercise and physiotherapy
  • NSAIDs and corticosteroids
  • DMARDs (Methotrexate)
  • Biologics

Osteoarthritis is a degenerative joint disease caused by breakdown of cartilage.

  • Aging
  • Joint injury
  • Obesity
  • Genetics
  • Joint pain
  • Stiffness
  • Reduced movement
  • Joint sounds
  • Weight loss and exercise
  • Physiotherapy
  • NSAIDs
  • Joint injections

Musculoskeletal disorders like RA and OA require long-term management with lifestyle changes and pharmacotherapy to improve quality of life.

An autoimmune disease causing joint inflammation.

A degenerative joint disease due to cartilage breakdown.

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