1. INTRODUCTION TO BIOCHEMISTRY

Biochemistry is the branch of science that studies the chemical processes occurring within living organisms. It explains how various molecules interact and coordinate to maintain life processes such as growth, metabolism, reproduction, and response to the environment.

The term Biochemistry was introduced by Carl Neuberg in 1903. This discipline integrates concepts from biology, chemistry, and physics to explain the structure, function, and behavior of biomolecules.

Biochemistry mainly deals with the study of:

  • Carbohydrates
  • Proteins
  • Lipids
  • Nucleic acids (DNA and RNA)
  • Enzymes and hormones

In simple terms, biochemistry is the chemistry of life. It helps us understand how the human body functions at the molecular level.

In pharmacy, biochemistry plays a crucial role in understanding how drugs interact with biological systems. It provides the molecular basis for drug action and therapeutic effects.

Biochemistry helps pharmacists and pharmaceutical scientists to:

  • Understand how diseases develop at the molecular level.
  • Design and develop new drug molecules.
  • Study drug metabolism and toxicity.
  • Develop and interpret biochemical tests for diagnosis and monitoring.

Thus, biochemistry forms the foundation of pharmaceutical sciences and medical research.

The main objectives of studying biochemistry include:

  • Understanding the structure and function of biological molecules.
  • Studying metabolic pathways and energy production in cells.
  • Exploring genetic mechanisms such as DNA replication, transcription, and translation.
  • Identifying biochemical changes associated with diseases.
  • Applying biochemical knowledge in drug development, biotechnology, and healthcare.

Biochemistry is closely linked with various branches of pharmaceutical sciences. Its scope in pharmacy includes:

  • Drug Discovery and Development: Understanding biochemical targets helps in designing effective and specific drugs.
  • Pharmacokinetics and Pharmacodynamics: Explains drug absorption, distribution, metabolism, excretion, and mechanism of action.
  • Toxicology: Studies the harmful effects of drugs and chemicals at the molecular level.
  • Clinical Diagnosis: Biochemical tests are used to detect and monitor disease conditions.
  • Biotechnology: Supports genetic engineering and production of therapeutic proteins and vaccines.
  • Personalized Medicine: Helps tailor drug therapy based on genetic and biochemical variations among patients.

Biochemistry serves as a vital link between chemistry and life sciences. For pharmacy students, it provides the scientific foundation for understanding drug action, disease mechanisms, and clinical applications. In essence, biochemistry explains life at the molecular level, and pharmacy applies this knowledge to promote health and treat diseases.

Biochemistry is the study of chemical processes and substances that occur in living organisms. It is commonly called the chemistry of life.

The term biochemistry was introduced by Carl Neuberg in 1903.

Biochemistry helps pharmacy students understand how drugs work at the molecular level, how diseases develop, and how medicines are metabolized in the body.

The main biomolecules include carbohydrates, proteins, lipids, nucleic acids, enzymes, and hormones.

Biochemistry helps identify molecular targets and pathways involved in diseases, which is essential for designing safe and effective drugs.

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